Ethylene Oxide (EO) Sterilization

Explore EO Solutions

  1. Home

  2. caret-right icon

    Products & Services

  3. caret-right icon

    Life Science Sterilization & Cleaning Monitoring

  4. caret-right icon

    Ethylene Oxide Sterilization

Confident, Compliant EO Sterilization from Cycle Development to Routine Monitoring 

Partner with the EO sterilization experts. Mesa Labs delivers ISO-certified PCDs and Biological Indicators with validated nominal D-values, proven across hundreds of EO configurations worldwide.

  • Accelerate validation
  • Streamline monitoring
  • Pass audits with confidence
Sterile environment

Zero Guesswork. Total Sterility Assurance.

Process Challenge Devices (PCDs) provide biological validation of ethylene oxide sterilization. Mesa Labs PCDs have unique patented packaging effectively assessing actual microbial kill rather than just measuring process conditions. Choose Mesa Labs PCDs to have complete confidence in the resistance of all the components of your PCD from the packaging to BI.

Commercial PCDs

“We are currently using Mesa Labs PCDs for one sterilization cycle validation, and we feel they offer good performance based on our product density and price.”

- Sr. Engineer Sterility Assurance at a global pharma company

The Mesa Labs Advantage

Our PCD solutions are built for professionals who can’t afford cycle failures, delays, or compliance gaps.
Established D-values

Established nominal D-values for reliable validation

Each Mesa PCD is manufactured under strict controls with validated nominal D-values, ensuring consistent, reproducible results across validations and routine runs.
Certificate

Industry-leading quality & traceability

Full lot traceability, controlled materials, and ISO-certified manufacturing meet the demands of FDA, ISO 11135, and customer audits.
EO cycle

Optimized for any EO cycle

From low-resistance to high-challenge configurations, our calibrated PCDs match your product’s resistance profile—ideal for single-product lines and multi-customer contract sterilization facilities.
Shipping

Faster release decisions

Self-contained BI PCDs allow rapid result reads without lab transfer, supporting reduced incubation times and quicker product release.
Regulatory

Regulatory peace of mind

Designed and manufactured to help you meet ISO 11135 and global regulatory expectations for resistance, traceability, and lot control.
PCD Comparison Chart
Warehouse PCDs

“Without resistometer testing, homemade PCDs lack measurable D-values, essentially sterilizing without understanding actual lethality effectiveness. Commercial PCDs provide established D-values through ISO 18472 compliant resistometer testing, enabling quantitative process validation.”

Sterilization Microbiologist, at a Global Healthcare Company

Supporting Your Sterilization Workflow

Cycle development

Cycle development

Select from Mesa’s PCD Selection Set to match external challenge resistance to your internal product challenge device. Identify the optimal PCD configuration for efficient validation.
Validation

Validation

Use PCDs with established nominal D-values to prove cycle lethality at the half-cycle, per ISO 11135, while ensuring IPCD kill and EPCD challenge.
Monitoring

Routine monitoring

Employ your chosen PCD configuration externally for ongoing cycle assurance and consistent compliance.

Data and Evidence Hub

PCD device

“We are using Mesa Labs PCDs for BI sterility testing for routine validation studies, and we like that the labeling is clear and concise. Also, it’s great to have the option to use the adhesive on the back, specifically for 4.7, 5.2 and 6.7 PCDs. Their quality is fantastic.”

Sterilization Microbiologist, at a Global Healthcare Company

Ensure your next EO run passes, the first time

Let Mesa help you choose the right PCD for confident, compliant, and efficient sterilization.

Talk to a PCD Specialist